JOURNAL OF PERIODONTAL RESEARCH, cilt.40, sa.2, ss.168-175, 2005 (SCI-Expanded)
Background: Nitric oxide (NO) is synthesized from the conversion Of L-arginine to L-citrulline by NO synthase (NOS). Arginase, which is an arginine-depleting enzyme, can compete with NOS for the common substrate L-arginine and thus inhibit NO production.