Effectiveness of scaling and root planing versus modified Widman flap on nitric oxide synthase and arginase activity in patients with chronic periodontitis

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Gullu C., Ozmeric N., Tokman B., Elgun S., Balos M.

JOURNAL OF PERIODONTAL RESEARCH, cilt.40, sa.2, ss.168-175, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 2
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1111/j.1600-0765.2005.00784.x
  • Dergi Adı: JOURNAL OF PERIODONTAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.168-175
  • Anahtar Kelimeler: arginase, nitric oxide synthase, periodontal treatment, periodontitis, HUMAN GINGIVAL FIBROBLASTS, EXPRESSION, TISSUE, INFLAMMATION, CYTOKINES, DISEASE, SALIVA, ADULT
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Nitric oxide (NO) is synthesized from the conversion Of L-arginine to L-citrulline by NO synthase (NOS). Arginase, which is an arginine-depleting enzyme, can compete with NOS for the common substrate L-arginine and thus inhibit NO production.