METABOLİK SENDROM MODELİ


Creative Commons License

Türközkan N., Yılmaz C.

in: BILIMSEL ARAŞTIRMALARDA LABORATUVAR HAYVANLARI & DENEYSEL MODELLER, Mustafa ARSLAN EDITÖRLER Elvan ANADOL Abdullah Özer, Editor, Akademisyen Kitabevi, Ankara, pp.1-586, 2023

  • Publication Type: Book Chapter / Chapter Vocational Book
  • Publication Date: 2023
  • Publisher: Akademisyen Kitabevi
  • City: Ankara
  • Page Numbers: pp.1-586
  • Editors: Mustafa ARSLAN EDITÖRLER Elvan ANADOL Abdullah Özer, Editor
  • Gazi University Affiliated: Yes

Abstract

Metabolic syndrome; It is a condition characterized by hyperinsulinemia, dyslipidaemia, glucose intolerance, hypertension and insulin resistance. In addition to genetic research on metabolic syndrome, experimental models are being created with various diets, the most commonly used being fructose diets to investigate formation mechanisms and treatment methods. However, due to differences in the study plan, such as the strain of the rat used (Wistar, Sprague Dawley), the route and amount of fructose administration (10-20% with drinking water, oral administration), the age of the animals (young or adult), and differences in the duration of the experiment, Metabolic consequences vary.