DNA Repair and Detoxifying Gene Polymorphisms in Patients with Multiple Sclerosis and Dental Amalgam Fillings

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Elkama A., Orhan G., Alp O., Tosun G., Öztekin Z. N., Karahalil B.

Gazi Medical Journal, cilt.32, sa.1, ss.33-39, 2021 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.12996/gmj.2021.07
  • Dergi Adı: Gazi Medical Journal
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier
  • Sayfa Sayıları: ss.33-39
  • Anahtar Kelimeler: Metallothionein, genetic polymorphisms, OGG1, PCR-RFLP, AAS, metals, S-TRANSFERASE T1, OXIDATIVE STRESS, HEAVY-METALS, SUSCEPTIBILITY, EXPRESSION, DETOXIFICATION, METAANALYSIS, EXPOSURE, HEALTH, COPPER
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: The present study was designed to evaluate the influence of Metallothionein (MT), detoxifying (GSTs) and repair (OGG1, XRCC1) gene polymorphisms on the risk of Multiple Sclerosis (MS) related to metal exposure.