Akademik Veri Yönetim Sistemi
Int Arc Dent Sci., cilt.46, sa.2, ss.133-142, 2025 (Hakemli Dergi)
ABSTRACT Today advances in CAD/CAM technology have enabled the production of indirect monolithic restoration materials and increased their use in prosthodontics. CAD/CAM-formed materials that can be used monolithically include composites, feldspathic glass ceramics, leucite crystals glass ceramics, glass ceramics reinforced with lithium disilicate crystals, lithium disilicate ceramics doped with zirconia, hybrid ceramics, and zirconia. The mechanical and physical properties of restorative materials must be biocompatible with the oral environment and free of toxic substances that may cause harmful local effects or systemic reactions. Some of the expected properties of dental materials include aesthetics, ease of use, long clinical lifespan, durability, and biocompatibility. Cytotoxic substances can cause harmful tissue reactions ranging from postoperative sensitivity to irreversible pulp damage in both the short and long term. These materials should be tested in vivo or in vitro before use. This article aims to present the results of the mechanical and biological studies of monolithic hybrid and zirconia-doped ceramic materials and the biocompatibility and cytotoxicity values obtained in the materials. Keywords: Prosthodontics, hybrid ceramic, glass ceramic, biocompatibility, cytotoxicity