HLA Genotypes in Turkish Hematopoietic Cell Recipients and Likelihood of Finding a Matched Donor Through Family Searches

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Kaya Z., Gönen S., Çalışkan B., Kemer Z., Unal A. B., Degirmenci E.

EXPERIMENTAL AND CLINICAL TRANSPLANTATION, vol.17, no.6, pp.813-818, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 6
  • Publication Date: 2019
  • Doi Number: 10.6002/ect.2016.0135
  • Journal Name: EXPERIMENTAL AND CLINICAL TRANSPLANTATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.813-818
  • Keywords: Extended family donors, Stem cell transplantation, HAPLOTYPE FREQUENCIES, TRANSPLANTATION, PROBABILITY, ALLELES
  • Gazi University Affiliated: Yes

Abstract

Objectives: Allogeneic hematopoietic stem cell transplant is a life-saving treatment, but donor numbers in Turkey do not meet the increasing demand for this procedure. Here, our objectives were (1) to assess the frequency of HLA-matched related donors in the Turkish population and (2) to identify the HLA antigens and haplotypes that are most frequent in Turkey.