Serum M30 levels are associated with survival in advanced gastric carcinoma patients


Yaman E., Coskun U., Sancak B., Buyukberber S., Ozturk B., Benekli M.

INTERNATIONAL IMMUNOPHARMACOLOGY, cilt.10, sa.7, ss.719-722, 2010 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Konu: 7
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1016/j.intimp.2010.03.013
  • Dergi Adı: INTERNATIONAL IMMUNOPHARMACOLOGY
  • Sayfa Sayıları: ss.719-722

Özet

Background: Cytokeratin 18 (CK-18) is a cytoskeleton protein of epithelial cells which are released into the circulation during necrotic or apoptotic cell death. M30 detects caspase-cleaved neo-epitope of CK-18; whereas M 65 measures whole length intact protein. We aimed to evaluate the prognostic significance of serum M65 and M30 levels in patients with gastric carcinoma.