The aim of study is to determine the effect of science teacher candidates' academic self-efficacy beliefs towards their science motivation. This research was prepared by survey model. The sample of this research consists of 222 teacher candidates attending 1st, 2nd, 3rdand 4th grades of Gazi University, Department of Science Education. At the end of the study, findings reveal that teacher candidates who took from the overall scale and of the motivation scale towards science and from the academic self-efficacy scale are at the middle level. Also, it is determined that % 20 of teacher candidates' total variance related to their motivations towards science is explained with the academic self-efficacy belief. (c) 2011 Published by Elsevier Ltd. Open access under CC BY-NC-ND license.