Comparing Brain Magnetic Resonance Spectroscopy Findings of Pediatric Treatment-Naive Obsessive-Compulsive Disorder Patients with Healthy Controls


Yalcin O., Sener S., BOYUNAGA Ö. L., Saripinar E. G., Ogur T., Guney E., ...More

TURK PSIKIYATRI DERGISI, vol.22, no.4, pp.222-229, 2011 (SSCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.5080/u6564
  • Journal Name: TURK PSIKIYATRI DERGISI
  • Journal Indexes: Social Sciences Citation Index (SSCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.222-229
  • Keywords: Pediatric obsessive-compulsive disorder, magnetic resonance spectroscopy, neuroimaging, CAUDATE GLUTAMATERGIC CHANGES, MEDIAL THALAMIC CHOLINE, VOXEL-BASED MORPHOMETRY, MAJOR DEPRESSION, MATTER ABNORMALITIES, ANTERIOR CINGULATE, ACTIVATION, CHILDREN, METAANALYSIS, NEUROPSYCHOLOGY
  • Gazi University Affiliated: Yes

Abstract

Objective: It is believed that biochemical alterations in different brain regions are involved in the pathophysiology of obsessive-compulsive disorder (OCD) in children and adolescents. The aim of this study was to explore possible metabolic variations between pediatric OCD cases and healthy controls in brain regions which were implicated in OCD pathophysiology.