Preclinical evaluation of a novel intracerebral microinjection instrument permitting electrophysiologically guided delivery of therapeutics


Cunningham M., Bolay H. B. , Scouten C., Moore C., Jacoby D., Moskowitz M., ...More

NEUROSURGERY, vol.54, no.6, pp.1497-1507, 2004 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 6
  • Publication Date: 2004
  • Doi Number: 10.1227/01.neu.0000125007.03145.00
  • Title of Journal : NEUROSURGERY
  • Page Numbers: pp.1497-1507
  • Keywords: cerebral ischemia, electrophysiology, functional neurosurgery, intracerebral injection, microcannula, neural transplantation, stereotactic surgery, FETAL VENTRAL MESENCEPHALON, TRAUMATIC BRAIN-INJURY, DOPAMINE NEURONS, NEUROTROPHIC FACTOR, STRIATAL REINNERVATION, PARKINSONS-DISEASE, CAUDATE-NUCLEUS, CEREBRAL-CORTEX, GRAFT-SURVIVAL, TRANSPLANTATION

Abstract

OBJECTIVE: This series of studies was designed to evaluate the function of a new neurosurgical instrument for precision injection of therapeutics within the central nervous system.