Evaluation of alginate based mesalazine tablets for intestinal drug delivery

Tugcu-Demiroez F., Acartuerk F., Takka S., Konus-Boyunaga Ö. L.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, cilt.67, sa.2, ss.491-497, 2007 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 67 Sayı: 2
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.ejpb.2007.03.003
  • Dergi Adı: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.491-497
  • Anahtar Kelimeler: mesalazine, alginate, intestinal drug delivery, X-ray imaging, IN-VIVO EVALUATION, GUM MATRIX TABLETS, 5-AMINOSALICYLIC ACID, SODIUM ALGINATE, ULCERATIVE-COLITIS, CROHNS-DISEASE, MULTIPLE-UNIT, RELEASE, SYSTEMS, THEOPHYLLINE
  • Gazi Üniversitesi Adresli: Evet

Özet

The aim of this study was to develop the alginate based mesalazine tablets for intestinal delivery. Sodium alginate is a biocompatible, natural polymer with pH-sensitive gel-forming ability.