JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, vol.17, no.2, pp.145-149, 2005 (SCI-Expanded)
Objective. The mechanisms responsible for lung liquid clearance during the neonatal period result in switching of the lung epithelium from net secretion to net absorption following birth and driven by active Na+ absorption. Transient tachypnea of the newborn (TTN) is known as the most common consequence of inadequate neonatal lung liquid clearance. It has been reported that alveolar type II cells behaved as a target for atrial natriuretic peptide (ANP) which inhibits the amiloride-sensitive Na-channel activity. The objective of this study is to investigate serum ANP concentrations in infants with TTN.