New triterpenoidal alkaloids from Buxus sempervirens

Ata, A; Naz, S; Choudhary, MI; Atta-ur-Rahman, A; Sener, B; Turkoz, S

doi:10.1515/znc-2002-1-204

New triterpenoidal alkaloids from Buxus sempervirens

Ata A., Naz S., Choudhary M., Atta-ur-Rahman A., Sener B., Turkoz S.

ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES, cilt.57, ss.21-28, 2002 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 57
Basım Tarihi: 2002
Doi Numarası: 10.1515/znc-2002-1-204
Dergi Adı: ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.21-28
Anahtar Kelimeler: Buxus sempervirens, (+)-16 alpha, 31-diacetylbuxadine and (-)-N-b-demethylcyclomikuranine, CYCLOPROTOBUXINE-A
Gazi Üniversitesi Adresli: Hayır

Özet

Phytochemical studies on the ethanolic extract of the roots of Buxus sempervirens of Turkish origin have resulted in the isolation of two new triterpenoidal alkaloids, (+)-16alpha, 31-diacetylbuxadine (1), (-)-N-b-demethylcyclomikuranine (2) along with three known natural products, (-)-cyclomikuranine (3), (-)-cyclobuxophylline-K (4) and (+)-buxaquamarine (5) isolated for the first time from this species of genus Buxus. The structures of these new natural products were established on the basis of extensive spectroscopic studies. Compound 1 exhibited antibacterial activity against human pathogenic bacteria and weak phytotoxic activity against Lemna minor Linn.