MINI-REVIEWS IN MEDICINAL CHEMISTRY, vol.20, no.11, pp.1042-1060, 2020 (SCI-Expanded)
Article / Article
MINI-REVIEWS IN MEDICINAL CHEMISTRY
Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
Alzheimer's disease, AChE inhibitor, BChE inhibitor, 3(2H)-Pyridazinone, hydrazone, molecular docking, ACETYLCHOLINESTERASE, BUTYRYLCHOLINESTERASE, DESIGN, INHIBITION, NARINGENIN, ANALOGS, COMPLEX, MTDLS
Gazi University Affiliated:
Background: Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are known to be serine hydrolase enzymes responsible for the hydrolysis of acetylcholine (ACh), which is a significant neurotransmitter for regulation of cognition in animals. Inhibition of cholinesterases is an effective method to curb Alzheimer's disease, a progressive and fatal neurological disorder.