Comparative efficacy of once-daily therapy with inhaled corticosteroid, leukotriene antagonist or sustained-release theophylline in patients with mild persistent asthma

Yurdakul A., Taci N., Eren A., Sipit T.

RESPIRATORY MEDICINE, cilt.97, sa.12, ss.1313-1319, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 97 Sayı: 12
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1016/j.rmed.2003.07.007
  • Dergi Adı: RESPIRATORY MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1313-1319
  • Anahtar Kelimeler: asthma, budesonide, montelukast, theophylline, treatment, MODERATE ASTHMA, BUDESONIDE, MONTELUKAST, SALBUTAMOL
  • Gazi Üniversitesi Adresli: Evet

Özet

The purpose of this study was to compare the efficacy and safety of the inhaled budesonide, sustained-release theophylline and montelukast, a leukotriene receptor antagonist, in patients with mild persistent asthma. In this single-center, randomized, parallel-group study that not designed blindly and placebo-controlled manner, 74 patients with mild persistent asthma were treated with either inhaled budesonide 400 mug once daily, oral montelukast 10 mg once daily, or sustained-release theophylline 400 mg once daily for 3 months.