Effects of Rat Bone Marrow-Derived Mesenchymal Stem Cells and Demineralized Bone Matrix on Cranial Bone Healing

Kandal S., Ozmen S., Uygur S., Yagci M., KAYHAN H., ELMAS Ç., ...More

ANNALS OF PLASTIC SURGERY, vol.77, no.2, pp.249-254, 2016 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 77 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.1097/sap.0000000000000274
  • Journal Name: ANNALS OF PLASTIC SURGERY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.249-254
  • Keywords: rat bone marrow-derived mesenchymal stem cells, demineralized bone matrix, cranial bone healing, MORPHOGENETIC PROTEIN-4, DEFECTS, GRAFT, DURA

Abstract

Background: Studies in tissue engineering about mesenchymal stem cells (MSCs) provide promising results for bone regeneration. The aim of this study was to evaluate the effects of rat bone marrow-derived MSCs (rMSCs) alone and when combined with demineralized bone matrix (DBM) on critical-sized cranial defects of rats.