Predictive factors for the development of brain metastases in patients with malignant melanoma: a study by the Anatolian society of medical oncology


Gumusay O., Coskun U., Akman T., Ekinci A. S., Kocar M., Erceleb O. B., ...More

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, vol.140, no.1, pp.151-157, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 140 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.1007/s00432-013-1553-7
  • Journal Name: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.151-157
  • Keywords: Melanoma, Brain metastases, Predictive factors, CENTRAL-NERVOUS-SYSTEM, CEREBRAL METASTASES, CUTANEOUS MELANOMA, PROGNOSTIC-FACTORS, THERAPY, SURVIVAL, LYMPHADENECTOMY, FEATURES, TRIAL, STAGE
  • Gazi University Affiliated: Yes

Abstract

The development of brain metastases (BMs) was associated with poor prognosis in melanoma patients. Patients with BMs have a median survival of < 6 months. Melanoma is the third most common tumor to metastasize to the brain with a reported incidence of 10-40 %. Our aim was to identify factors predicting development of BMs and survival.