Retinitis Pigmentosa and Spontaneous Lens Resorption
TURK OFTALMOLOJI DERGISI-TURKISH JOURNAL OF OPHTHALMOLOGY, cilt.35, sa.1, ss.41-47, 2005 (ESCI, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 35 Sayı: 1
- Basım Tarihi: 2005
- Dergi Adı: TURK OFTALMOLOJI DERGISI-TURKISH JOURNAL OF OPHTHALMOLOGY
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.41-47
- Gazi Üniversitesi Adresli: Evet
Özet
Purpose: Definition of two brothers with retinitis pigmentosa and spontaneous lens resorption. Methods: A 25 year old male patient with the complaint of progressive decreased night vision in both eyes and severely decreased vision in the right eye had been accepted at our outpatient clinic. In his pedigree analysis it was noticed that his mother and father were first degreee relatives, he had two brothers affected like him and three sisters who had been exitus at about 2 years of age. The patient and one of his affected brothers had full ophthalmological examination, fundus fluorescein angiography, ultrasonography and electrophysiological tests. Results: His visual acuities were light perception and 0.05 on the right and left eyes respectively. On anterior segment examination lens material could not be seen other than the opasified lens capsule and secclusio pupilla was observed on the right side. On the left eye, there was microspherophakia and corticonucleer cataract. During fundus examination, the right fundus was not visible while arterial narrowing, optic atrophy, bone spicule pigmentation and sequels of cystoid macular edema were viewed on the left eye. With A-scan ultrasonography the axial diameters of both eyes were normal. At electrophysiology the amplitudes were so low that they could not be measured. After removing his lens material with cataract by phakoemulsification his visual acuity increased to 0.2 on the left eye. The acuity on the right eye did not improve after applying YAG capsulotomy. The brother examined could see only hand motion with the left eye while the right eye had no light perception. On ophthalmological examination in both eyes lens material could not be seen other than the opasified lens capsule and fundus findings of the left eye were identical to those of his brother. With A-scan ultrasonography and electrophysiology the findings were similar to those of his brother. Conclusion: In the literature lens pathologies seen in combination with retinitis pigmentosa are limited especially with posterior subcapsular cataract. To our knowledge our patient and his brother are the first retinitis pigmentosa cases with spontaneous lens resorption that is the dissolution of normal lens without a history of trauma or surgery.