Effects of Nuclear Factor-kappa B Inhibitors on Colon Anastomotic Healing in Rats

BEDİRLİ, ABDULKADİR; Salman, Bulent; PAŞAOĞLU, HATİCE; Ofluoglu, Ebru; ŞAKRAK, ÖMER

doi:10.1016/j.jss.2010.01.028

Effects of Nuclear Factor-kappa B Inhibitors on Colon Anastomotic Healing in Rats

BEDİRLİ A., Salman B., PAŞAOĞLU H., Ofluoglu E., ŞAKRAK Ö.

JOURNAL OF SURGICAL RESEARCH, cilt.171, sa.1, ss.355-360, 2011 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 171 Sayı: 1
Basım Tarihi: 2011
Doi Numarası: 10.1016/j.jss.2010.01.028
Dergi Adı: JOURNAL OF SURGICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.355-360
Anahtar Kelimeler: anastomosis, healing, colon, NF-kappa B, matrix metalloproteinases, MATRIX METALLOPROTEINASES, MICE, ACTIVATION, MECHANISMS, EXPRESSION, CYTOKINES, RECEPTOR
Gazi Üniversitesi Adresli: Evet

Özet

Background. Nuclear factor (NF)-kappa B plays an essential role in inflammation. We tested this role by administering NF-kappa B-inhibitors into rats undergoing a well-established model of colonic anastomotic healing.