Effects of Nuclear Factor-kappa B Inhibitors on Colon Anastomotic Healing in Rats


BEDİRLİ A. , Salman B., PAŞAOĞLU H. , Ofluoglu E., ŞAKRAK Ö.

JOURNAL OF SURGICAL RESEARCH, vol.171, no.1, pp.355-360, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 171 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.1016/j.jss.2010.01.028
  • Title of Journal : JOURNAL OF SURGICAL RESEARCH
  • Page Numbers: pp.355-360
  • Keywords: anastomosis, healing, colon, NF-kappa B, matrix metalloproteinases, MATRIX METALLOPROTEINASES, MICE, ACTIVATION, MECHANISMS, EXPRESSION, CYTOKINES, RECEPTOR

Abstract

Background. Nuclear factor (NF)-kappa B plays an essential role in inflammation. We tested this role by administering NF-kappa B-inhibitors into rats undergoing a well-established model of colonic anastomotic healing.