©Copyright 2021 by Gazi University Medical FacultyOne of the most common symptoms of ovarian cancer is ascites and can be controlled by surgery and chemotherapy. Acid palliation is provided with paracentesis and diuretic therapy in treatment-resistant patients. Chylous acid is rarely detected in the course of ovarian cancer and it mostly develops due to lymphatic system damage due to surgery or radiotherapy. Chylous acid due to disease progression is an extremely rare phenomenon. A 71-year-old woman with metastatic ovarian cancer presented with abdominal distension and milky acid. The patient has not received chemotherapy for about 3 months due to COVID-19 infection. After the infectious causes were excluded, the patient was started second line therapy and it was observed that chylous acid regressed. When chylous acid is detected in a cancer patient, infectious causes should be excluded quickly and systemic anti-cancer treatment should be initiated.