Serum zinc, insulin-like growth factor-I and insulin-like growth factor binding protein-3 levels in children with type 1 diabetes mellitus

Bideci A., Camurdan M. O., Cinaz P., Dursun H., Demirel F.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.18, sa.10, ss.1007-1011, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 10
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1515/jpem.2005.18.10.1007
  • Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1007-1011
  • Anahtar Kelimeler: zinc, IGF-I, IGFBP-3, type I diabetes mellitus, children, HORMONE, AXIS
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Growth is impaired during the course of diabetes mellitus (DM). Derangement of the growth hormone/insulin-like growth factor (IGF) axis, insulinopenia and zinc deficiency are the possible causative factors of this impairment. Zn supplementation is proven to attenuate hyperglycemia in mice but its use to ameliorate impaired height is still a matter of discussion.