Comparison of antioxidant activities of aminoguanidine, methylguanidine and guanidine by luminol-enhanced chemiluminescence

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Yildiz G., Demiryurek A., Sahin-Erdemli I., Kanzik I.

BRITISH JOURNAL OF PHARMACOLOGY, vol.124, no.5, pp.905-910, 1998 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 124 Issue: 5
  • Publication Date: 1998
  • Doi Number: 10.1038/sj.bjp.0701924
  • Journal Name: BRITISH JOURNAL OF PHARMACOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.905-910
  • Keywords: chemiluminescence, aminoguanidine, methylguanidine, guanidine, free radicals, peroxynitrite, antioxidant activity, NITRIC-OXIDE SYNTHASE, PEROXYNITRITE, PROPOFOL, FAILURE, INJURY, TISSUE, CELLS
  • Gazi University Affiliated: No

Abstract

1 The objective of this study was to investigate the ability of aminoguanidine, methylguanidine and guanidine to inhibit free radicals or metabolites generated by either stimulated human leucocytes or cell-free systems using luminol-enhanced chemiluminescence (CL).