As cardioprotective and angiogenic biomarker, can ghrelin level predict coronary collateral development and severity of coronary atherosclerosis?

Akboga M. K., Tacoy G., Demirtas C., TÜRKOĞLU S., Boyaci B., Cengel A.

TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, vol.45, no.4, pp.316-323, 2017 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 4
  • Publication Date: 2017
  • Doi Number: 10.5543/tkda.017.96169
  • Journal Name: TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.316-323
  • Keywords: Anjiyogesis: ghrelin, good collateral development, SYNTAX score, vascular endothelial growth factor A, MICROVASCULAR ENDOTHELIAL-CELLS, STIMULATES ANGIOGENESIS, ARTERY-DISEASE, CIRCULATION, GROWTH, HEART, ACTIVATION, ISCHEMIA, HORMONE, MODEL
  • Gazi University Affiliated: Yes

Abstract

Objective: Ghrelin is expressed in the cardiovascular system and exerts protective effects, including inhibiting progression of atherosclerosis, suppression of vascular inflammation, and stimulating angiogenesis. The aim of this study was to investigate the effect of serum ghrelin on coronary collateral development and SYNTAX score in patients with severe coronary artery disease.