The Effect of Temozolomide on the Prevention of Epidural Fibrosis Developing after Lumbar Laminectomy in Rats

Creative Commons License

Aydincak O., Yilmaz M. B. , Emmez H., KURT G. , SEPİCİ DİNÇEL A. , Memis L., ...Daha Fazla

TURKISH NEUROSURGERY, cilt.22, sa.6, ss.706-711, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Konu: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.5137/1019-5149.jtn.5966-12.1
  • Sayfa Sayıları: ss.706-711


AIM: Failed back surgery syndrome is observed in 15% of patients who have undergone surgery for lumbar disk hernia. Excess epidural fibrosis is the etiology in 24% of FBSS cases. This study was conducted with the belief that the antiproliferative effect of temozolomide can prevent epidural fibrosis.