Histopathological Effects of Teriparatide in Medication-Related Osteonecrosis of the Jaw: An Animal Study


Keskinruzgar A., Bozdag Z., Aras M. H. , DEMİR T., YOLCU Ü., ÇETİNER S.

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, vol.74, no.1, pp.68-78, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 74 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.1016/j.joms.2015.07.005
  • Title of Journal : JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
  • Page Numbers: pp.68-78

Abstract

Purpose: Osteonecrosis of the jaw after tooth extraction is a major complication in patients using bisphosphonates (BPs) for bone lesions, such as for the treatment of osteoporosis. The purpose of this study was to investigate the histopathologic effects of teriparatide (a synthetic parathyroid hormone) on rats developing osteonecrosis with BP use.