Akademik Veri Yönetim Sistemi
Multiple Sclerosis and Related Disorders, cilt.101, 2025 (SCI-Expanded)
Aim: The aim of this dietary intervention study is to evaluate the effect of the MIND diet on oxidative stress markers and nutritional status in patients with Multiple sclerosis (MS). Methods: The study was conducted on 30 participants aged of 20–45 who were diagnosed with Relapsing-remitting MS. After the initial evaluation, healthy nutrition recommendations were given to the participants through a MIND diet sample menu list for 8 weeks. At the end of the study, all measurements were repeated. Results: The mean score of MIND diet adherence questionnaire and serum total antioxidant status level increased significantly at the end of the eighth week (p < 0.001 and p < 0.05). Although the results were not significant, serum superoxide dismutase, catalase and glutathione peroxidase levels tended to increase. In females, there was a significant decrease in body weight, body mass index, waist circumference and total body bone-free lean mass at the end of the study (p < 0.05). In addition, mean daily protein intake and protein intake per kg increased significantly in males (p = 0.028 for both variables) and dietary fiber intake increased significantly (p = 0.047) in all participants. Conclusion: This study showed that the MIND diet may has positive effects on increasing the defense system against inflammation and oxidative stress.