The effect of EGF application in gel form on histamine content of experimentally induced wound in mice

Babul A., Gonul B., Dincer S. , Erdogan D., Ozogul C.

AMINO ACIDS, cilt.27, ss.321-326, 2004 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1007/s00726-004-0103-7
  • Dergi Adı: AMINO ACIDS
  • Sayfa Sayıları: ss.321-326


The factors participating to the wound healing are complex and still obscure. Among these factors, epidermal growth factor (EGF) and histamine by increasing reepithelization and reparation tissue strength via enhancing collagen deposition to the wound site have a beneficial effect. This study was performed to investigate the effect of EGF dosage forms on the histamine content of the experimentally induced wound and some wound healing criters in the mice.