Anticoagulation Management with Bivalirudin in a Case with Heparin Resistance Detected During Coronary Artery Bypass Surgery Koroner Arter Bypass Cerrahisinde Heparin Direnci Tespit Edilen Olguda Bivalirudin ile Antikoagulasyon Yönetimi

Creative Commons License

KARAKAYA E., ACU N., Özdemirkan A., TAK S., ÜNAL Y.

Anestezi Dergisi, cilt.32, sa.3, ss.182-186, 2024 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 3
  • Basım Tarihi: 2024
  • Doi Numarası: 10.54875/jarss.2024.69772
  • Dergi Adı: Anestezi Dergisi
  • Derginin Tarandığı İndeksler: Scopus, Academic Search Premier, Central & Eastern European Academic Source (CEEAS), EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.182-186
  • Anahtar Kelimeler: anticoagulants, bivalirudin, cardiopulmonary bypass, Heparin
  • Gazi Üniversitesi Adresli: Evet

Özet

Heparin is commonly used during cardiopulmonary bypass for anticoagulation. However, despite its status as the gold standard, there are limitations. It is contraindicated in patients allergic to heparin or protamine, as well as those with heparin-induced thrombocytopenia. Bivalirudin, a direct thrombin inhibitor, has been reported as a safe and effective alternative in cases where heparin cannot be used due to these contraindications. Here, we present our experience using bivalirudin in a patient diagnosed with heparin resistance.