Exploring Turkish biodiversity: A rich source of chemical diversity for drug leads discovery


Sener B., ERDOĞAN ORHAN İ.

PURE AND APPLIED CHEMISTRY, vol.83, no.9, pp.1699-1707, 2011 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 83 Issue: 9
  • Publication Date: 2011
  • Doi Number: 10.1351/pac-con-11-02-01
  • Journal Name: PURE AND APPLIED CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1699-1707
  • Keywords: biodiversity, biological activity, drug discovery, medicinal chemistry, natural products, structure-activity, ANTIOXIDANT ACTIVITIES, INHIBITORY-ACTIVITY, ACETYLCHOLINESTERASE, BUTYRYLCHOLINESTERASE, PLANTS, L., DERIVATIVES, TAXA

Abstract

Bioresources offer tremendous potential by having excellent chemical diversity for drug discovery programs and by serving as templates for synthetic drugs. There are well- known examples of clinically important drugs derived from natural sources. The development of pharmaceutical, nutraceutical, agricultural, and industrial products from bioresources can be used to promote incentives for conservation by providing an economic return to innovative use. Of those sources, medicinal plants have a virtually untapped reserve of original drug molecules, which await determination and chemical and biological investigation. Marine organisms have also gained increasing attention from researchers worldwide due to their chemically diverse secondary metabolites with desirable biological activities.