First report on phytochemical content and biological activities of seseli salsugineum A. Duran & lyskov: a new endemic species

Önder A., Doğan Güner E., Saritas M., Trendafilova A., Tekşen M., Zengin G.

Natural Product Research, 2025 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1080/14786419.2025.2511167
  • Dergi Adı: Natural Product Research
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Aquatic Science & Fisheries Abstracts (ASFA), Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, CINAHL, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: antioxidant, coumarins, enzyme inhibitors, pyranocoumarins, Seseli
  • Gazi Üniversitesi Adresli: Evet

Özet

Five pyranocoumarins (1-5) together with a simple coumarin, umbelliferone (6), have been isolated from Seseli salsugineum A. Duran & Lyskov, a newly described endemic species for Türkiye, and their structural elucidation was performed by spectroscopic analysis and comparison with the literature data. In addition, hexane, dichloromethane (DCM), and methanol (MeOH) extracts were examined for their antioxidant and enzyme inhibition potentials. The current study is the first report on an endemic S. salsugineum, regarding interesting bioactive coumarins (pyranocoumarins and a simple coumarin) and the extract’s biological properties. Further research is needed to isolate new compounds from this plant and uncover its potential uses as a health-promoting and healing agent.