Cyclooxygenase-2 expression and its association with angiogenesis, Helicobacter pylori, and clinicopathologic characteristics of gastric carcinoma


Yamac D., Ayyildiz T., Coskun U., AKYÜREK N., DURSUN A., Seckin S., ...More

PATHOLOGY RESEARCH AND PRACTICE, vol.204, no.8, pp.527-536, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 204 Issue: 8
  • Publication Date: 2008
  • Doi Number: 10.1016/j.prp.2008.01.002
  • Journal Name: PATHOLOGY RESEARCH AND PRACTICE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.527-536
  • Gazi University Affiliated: Yes

Abstract

Cyclooxygenase-2 (COX-2) is upregulated in gastric carcinoma, and its increased levels were found to have a prognostic significance in some studies. Both angiogenesis and Helicobacter pylori infection have been reported to be associated with COX-2 expression of gastric cancer in recent studies.