Cyclooxygenase-2 expression and its association with angiogenesis, Helicobacter pylori, and clinicopathologic characteristics of gastric carcinoma

Yamac D., Ayyildiz T., Coskun U., AKYÜREK N., DURSUN A., Seckin S., ...Daha Fazla

PATHOLOGY RESEARCH AND PRACTICE, cilt.204, sa.8, ss.527-536, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 204 Sayı: 8
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.prp.2008.01.002
  • Dergi Adı: PATHOLOGY RESEARCH AND PRACTICE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.527-536
  • Anahtar Kelimeler: COX-2, angiogenesis, CD31, H.-pylori, gastric cancer, ENDOTHELIAL GROWTH-FACTOR, NITRIC-OXIDE SYNTHASE, TUMOR ANGIOGENESIS, GENE-EXPRESSION, UP-REGULATION, ASPIRIN USE, CANCER, OVEREXPRESSION, INFECTION, STOMACH
  • Gazi Üniversitesi Adresli: Evet

Özet

Cyclooxygenase-2 (COX-2) is upregulated in gastric carcinoma, and its increased levels were found to have a prognostic significance in some studies. Both angiogenesis and Helicobacter pylori infection have been reported to be associated with COX-2 expression of gastric cancer in recent studies.