The impact of reconstruction and scanner characterisation on the diagnostic capability of a normal database for [I-123]FP-CIT SPECT imaging

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Dickson J. C., Tossici-Bolt L., Sera T., Booij J., Ziebell M., Morbelli S., ...Daha Fazla

EJNMMI RESEARCH, cilt.7, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1186/s13550-016-0253-0
  • Dergi Adı: EJNMMI RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: [I-123]FP-CIT, SPECT, Quantification, Reconstruction, Dopamine transporter, HEALTHY CONTROLS, BINDING RATIO, TOMOGRAPHY, DISEASE, IMAGES
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: The use of a normal database for [I-123]FP-CIT SPECT imaging has been found to be helpful for cases which are difficult to interpret by visual assessment alone, and to improve reproducibility in scan interpretation. The aim of this study was to assess whether the use of different tomographic reconstructions affects the performance of a normal [I-123] FP-CIT SPECT database and also whether systems benefit from a system characterisation before a database is used.