An autopsy case of disseminated angioinvasive aspergillosis


Samdanci E., Ak S., Bozdag Z., Sayin S.

Egyptian Journal of Forensic Sciences, cilt.2, sa.1, ss.38-41, 2012 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 2 Sayı: 1
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.ejfs.2011.12.003
  • Dergi Adı: Egyptian Journal of Forensic Sciences
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.38-41
  • Anahtar Kelimeler: Angioinvasive, Aspergillosis, Autopsy, Diabetes mellitus, Hyphae, Medico-legal
  • Gazi Üniversitesi Adresli: Hayır

Özet

© 2012 Forensic Medicine Authority.Angioinvasive aspergillosis is a rare but potentially devastating disease especially in immunocompromised hosts. However diabetes mellitus is one of the chronic conditions that leads to immunosufficiency in patients, it is rarely reported in such cases. Here we aimed to present an autopsy case of disseminated angioinvasive aspergillosis with diabetes mellitus and discuss the other possible underlying reasons for this situation. A 52. year old man with diabetes mellitus operated for the fracture of his L1 vertebra and tibia due to falling down from the third floor of a building. After his death on postoperative 34th day, histopathologic examination of the tissue samples presented multiple hyphae having dichotomous branching at 45-degree angles in infiltration areas. In conclusion, in long-term hospitalized patients with diabetes mellitus, fungal infections should be taken into account and an empirical antifungal therapy is recommended. Besides, sterilization procedures should be obeyed in order to prevent infectious diseases.