A novel wound healing ointment: A formulation of Hypericum perforatum oil and sage and oregano essential oils based on traditional Turkish knowledge

SÜNTAR İ., AKKOL E., KELEŞ H., Oktem A., BAŞER K. H. C., YEŞİLADA E.

JOURNAL OF ETHNOPHARMACOLOGY, cilt.134, sa.1, ss.89-96, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 134 Sayı: 1
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.jep.2010.11.061
  • Dergi Adı: JOURNAL OF ETHNOPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.89-96
  • Anahtar Kelimeler: Excision wound, Hypericum perforatum, Incision wound, Medicinal plants, Origanum majorana essential oil, Origanum minutiflorum essential oil, Olive oil, Salvia triloba essential oil, Tensiometer, Wound healing, FOLK MEDICINE, TURKEY, ANATOLIA, PLANTS
  • Gazi Üniversitesi Adresli: Evet

Özet

Aim of the study: Hypericum perforatum L (Hypericaceae), olive oil (Oleaceae), Origanum Tourn ex L and Salvia L. species (Lamiaceae) are used against inflammatory disorders and for healing of skin wounds in traditional Turkish medicine. A new ointment formulation was developed to provide more efficient wound healing activity. The content of the formulation was as follows; olive oil extract of flowering aerial parts of Hypericum perforatum L, olive oil, an equivalent mixture of Origanum majorana L and Origanum minutiflorum Schwrd. et Davis essential oils (Origani aetheroleum), Salvia triloba L essential oil. The aim of the present study is to assess the wound healing potential of this new formulation by using in vivo and in vitro models as well as histopathological methods.