Evaluation of clinical and laboratory findings in severe group COVID-19 pregnants without comorbidity

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Bozkurt F., Coşkun Ö., Yeleç S., Bekçibaşi M., Asena M., Bağli İ.

Turkish Journal of Medical Sciences, vol.52, no.1, pp.11-20, 2022 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.3906/sag-2105-116
  • Journal Name: Turkish Journal of Medical Sciences
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.11-20
  • Keywords: COVID-19, pregnancy, ferritin, severe disease, 3rd trimester, PNEUMONIA
  • Gazi University Affiliated: No


© TÜBİTAK.Background/aim: COVID-19 disease may be seen with different clinical presentations in pregnant women. Comorbid diseases are important factors affecting the progression of this disease. In this study, we aimed to evaluate the clinical and laboratory findings in pregnant women with COVID-19 who had no comorbid disease. Material and methods: This retrospective designed study included 217 patients with Covid PCR positive in typically COVID-19 clinic. The patients were classified into asymptomatic, nonsevere, and severe disease groups. The symptoms, laboratory results, hospital follow-ups and intensive care records of the patients and the findings of new borns are presented. Results: Most of the patients (78%) were in the third trimester of pregnancy, and 103 patients in the study group had severe disease. Fever in the non-severe group and respiratory distress in the severe group were the most common symptoms in the patients. The severe clinical manifestations were specifically observed in the third trimester patients. In the severe group, neutrophil, lactat dehydrogenase, ferritin, CK-MB, IL – 6, and hospital stay were statistically higher than those in other groups (p < 0.05). Increase in BUN and creatine were the most predictive parameters in intensive care admission. While the intensive care unit (ICU) requirement was higher in patients in the severe group, premature birth was observed more frequently in the severe group (p < 0.05). Conclusion: COVID-19 positive pregnant women were mostly detected in the third trimester, and the disease was more severe in this period. Also, the need for intensive care, the rate of delivery by caesarean section, and the rate of preterm delivery of these pregnant women were also found to be high.