Ultrastructural damage in lung tissues in rats treated with doxorubicin and paclitaxel

TAKE KAPLANOĞLU, GÜLNUR; Yamac, Deniz; Ozogul, Candan; Erdogan, Deniz

doi:10.1007/s12325-008-0015-0

Ultrastructural damage in lung tissues in rats treated with doxorubicin and paclitaxel

TAKE KAPLANOĞLU G., Yamac D., Ozogul C., Erdogan D.

ADVANCES IN THERAPY, cilt.25, sa.2, ss.115-122, 2008 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 25 Sayı: 2
Basım Tarihi: 2008
Doi Numarası: 10.1007/s12325-008-0015-0
Dergi Adı: ADVANCES IN THERAPY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.115-122
Anahtar Kelimeler: antitumoural agent, electron microscopy, lung, CANCER, CHEMOTHERAPY
Gazi Üniversitesi Adresli: Evet

Özet

Introduction: The aim of this study was to determine the ultrastructural effects of doxorubicin ( Adriblastina (R); Pharmacia and Upjohn, Milan, Italy), paclitaxel ( Taxol (R); BMS, Princeton, NJ), Cremophor (R) EL ( a diluent of paclitaxel) and doxorubicin/ paclitaxel combinations on normal lung tissues.