Ultrastructural damage in lung tissues in rats treated with doxorubicin and paclitaxel

TAKE KAPLANOĞLU G., Yamac D., Ozogul C., Erdogan D.

ADVANCES IN THERAPY, vol.25, no.2, pp.115-122, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 2
  • Publication Date: 2008
  • Doi Number: 10.1007/s12325-008-0015-0
  • Journal Name: ADVANCES IN THERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.115-122
  • Keywords: antitumoural agent, electron microscopy, lung, CANCER, CHEMOTHERAPY
  • Gazi University Affiliated: Yes

Abstract

Introduction: The aim of this study was to determine the ultrastructural effects of doxorubicin ( Adriblastina (R); Pharmacia and Upjohn, Milan, Italy), paclitaxel ( Taxol (R); BMS, Princeton, NJ), Cremophor (R) EL ( a diluent of paclitaxel) and doxorubicin/ paclitaxel combinations on normal lung tissues.