Neuroprotective Effects of Vigabatrin on Spinal Cord Ischemia-Reperfusion Injury

Durdag, Emre; Yildirim, Zuhal; Unlu, Nese; KALE, AYDEMİR; Ceviker, Necdet

doi:10.1016/j.wneu.2018.07.103

Neuroprotective Effects of Vigabatrin on Spinal Cord Ischemia-Reperfusion Injury

Atıf İçin Kopyala

Durdag E., Yildirim Z., Unlu N. L., KALE A., Ceviker N.

WORLD NEUROSURGERY, cilt.120, 2018 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 120
Basım Tarihi: 2018
Doi Numarası: 10.1016/j.wneu.2018.07.103
Dergi Adı: WORLD NEUROSURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Anahtar Kelimeler: Antioxidants, Oxidative stress, Rabbit, Spinal cord injury, Vigabatrin, LIPID-PEROXIDATION, ANTIEPILEPTIC DRUGS, PATHOPHYSIOLOGY, GLUTATHIONE, MECHANISMS, BREAST, GABA
Gazi Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Spinal cord ischemia is a serious and catastrophic clinicopathologic condition. Despite studies reported over the last 20 years, alternative and efficient treatment options remain unclear. We examined the neuroprotective effects of vigabatrin on a spinal ischemia-reperfusion model.