Neuroprotective Effects of Vigabatrin on Spinal Cord Ischemia-Reperfusion Injury

Durdag E., Yildirim Z., Unlu N. L., KALE A., Ceviker N.

WORLD NEUROSURGERY, cilt.120, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 120
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.wneu.2018.07.103
  • Dergi Adı: WORLD NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Antioxidants, Oxidative stress, Rabbit, Spinal cord injury, Vigabatrin, LIPID-PEROXIDATION, ANTIEPILEPTIC DRUGS, PATHOPHYSIOLOGY, GLUTATHIONE, MECHANISMS, BREAST, GABA
  • Gazi Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Spinal cord ischemia is a serious and catastrophic clinicopathologic condition. Despite studies reported over the last 20 years, alternative and efficient treatment options remain unclear. We examined the neuroprotective effects of vigabatrin on a spinal ischemia-reperfusion model.