The aim of this study is to investigate the effects of impregnation chemicals on the weight loss during combustion of Laminated Veneer Lumber (LVL) obtained from combination of Oriental beech + Lombardy poplar and European oak + Lombardy poplar woods, impregnated with Borax (Bx), Boric acid (Ba), Bx+Ba (wt:wt 50:50%), Imersol-aqua and Timbercare-aqua according to ASTM D 1413. The LVL samples were prepared in the form of five layers, 3 mm thickness from the beech, oak and poplar veneers bonded with Desmodur-VTKA and Poly(vinyl acetate) adhesives, according to TS EN 386. The weight loss during combustion of the LVL test samples was determined according to ASTM E 160. Consequently, the weight loss percentage was the highest in beech-poplar combination processed with Imersol-aqua and DVTKA and the lowest in oak-poplar combination, Ba+Bx and PVAc adhesive. In the interaction of the wood materials, impregnation chemicals and adhesive types, it was the highest in beech-poplar combination + Timbarecare-aqua + DVTKA and the lowest in beech-poplar combination + (Ba+Bx) + PVAc. As a result, it can be said that the type of impregnation material has a first degree efficacy and wood material have second degree efficacy on the weight loss. Thus, the weight loss was high in beech-poplar combination impregnated with Ta but low in the same wood material impregnated with Ba+Bx. Accordingly, for places which has fire risk, usage of LVL wood material impregnated with boron compounds would be advantageous.