Association Between A Body Shape Index and Probable Osteosarcopenia in Postmenopausal Women: Cross-Sectional Study Postmenapozal Kadınlarda Vücut Şekil İndeksi ile Muhtemel Osteosarkopeni Arasındaki İlişki: Kesitsel Çalışma
Turkiye Klinikleri Journal of Medical Sciences, cilt.46, sa.3, ss.258-265, 2026 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 46 Sayı: 3
- Basım Tarihi: 2026
- Doi Numarası: 10.5336/medsci.2026-118727
- Dergi Adı: Turkiye Klinikleri Journal of Medical Sciences
- Derginin Tarandığı İndeksler: Scopus, Central & Eastern European Academic Source (CEEAS), CINAHL, EMBASE, TR DİZİN (ULAKBİM), Biomedical Reference Collection: Corporate Edition (EBSCO), Health Research Premium Collection (ProQuest)
- Sayfa Sayıları: ss.258-265
- Anahtar Kelimeler: A Body Shape Index, handgrip strength, osteoporosis, osteosarcopenia, sarcopenia
- Gazi Üniversitesi Adresli: Evet
Özet
Objective: Osteosarcopenia, the coexistence of osteoporosis and sarcopenia, is a growing concern in postmenopausal women. A Body Shape Index (ABSI), a novel measure of abdominal adiposity, has been linked to metabolic and musculoskeletal disorders. Given the potential role of central adiposity in muscle and bone deterioration, this study aimed to evaluate the association between ABSI and probable osteosarcopenia. Material and Methods: This retrospective study included 605 postmenopausal older women. Probable osteosarcopenia was defined as the coexistence of osteoporosis (T-score ≤-2.5 at the lumbar spine or femoral neck) and low handgrip strength (<16 kg). ABSI was calculated as waist circumference (WC)/[body mass index (BMI2/3×height1/2)]. Multivariate logistic regression and ROC curve analysis were used to evaluate the association and dis-criminative ability of ABSI for probable osteosarcopenia. Results: The mean age of participants was 74.9±6.4 years. ABSI was higher in those with osteosarcopenia (p<0.001) and was independently associated with probable osteosarcopenia (OR=1.55, 95% CI 1.20-2.01, p=0.001). ABSI demon-strated moderate diagnostic accuracy (AUC=0.676, 95% CI 0.636-0.714, p<0.001) with a negative predictive value of 94.2%, outperforming WC (AUC=0.583, p=0.002) and BMI (AUC=0.622, p<0.001). DeLong’s test confirmed that ABSI performed significantly better than WC (p=0.0158) and BMI (p=0.0214), while no significant difference was found between BMI and WC (p=0.0742). Conclusion: ABSI is an independently associated with probable osteosarcopenia, outperforming BMI and WC. These findings suggest its potential as a screening tool, though further research is needed to confirm clinical applicability.