Gingival crevicular fluid levels of osteoprotegerin (OPG) in premenopausal and postmenopausal women with or without chronic periodontitis


Babur C., Ozcan G., Cebi D. U. , Pervane B., ÖZDEMİR B. , ATAK YÜCEL A. , ...Daha Fazla

JOURNAL OF DENTISTRY, cilt.40, sa.5, ss.364-371, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Konu: 5
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.jdent.2012.01.013
  • Dergi Adı: JOURNAL OF DENTISTRY
  • Sayfa Sayıları: ss.364-371

Özet

Objectives: Systemic conditions may affect host susceptibility, disease progression and severity as well as treatment response. Previously, low oestrogen (E-2) levels were associated with increased bone resorption, due to increased osteoclastogenesis and decreased osteoclast apoptosis. Osteoprotegerin (OPG) is an essential cytokine for osteoclastogenesis. The aim of this study was to evaluate gingival crevicular fluid (GCF) OPG levels in menopausal and premenopausal patients with or without periodontitis, and effects of phase I periodontal therapy on GCF OPG levels.