Gingival crevicular fluid levels of osteoprotegerin (OPG) in premenopausal and postmenopausal women with or without chronic periodontitis

Babur, Ceren; Ozcan, GÖNEN; Cebi, EMİN; Pervane, Beste; ÖZDEMİR, BURCU; ATAK YÜCEL, AYŞEGÜL; Biri, AYDAN; Babur, Cahit

doi:10.1016/j.jdent.2012.01.013

Gingival crevicular fluid levels of osteoprotegerin (OPG) in premenopausal and postmenopausal women with or without chronic periodontitis

Atıf İçin Kopyala

Babur C., Ozcan G., Cebi D. U., Pervane B., ÖZDEMİR B., ATAK YÜCEL A., ...Daha Fazla

JOURNAL OF DENTISTRY, cilt.40, sa.5, ss.364-371, 2012 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 40 Sayı: 5
Basım Tarihi: 2012
Doi Numarası: 10.1016/j.jdent.2012.01.013
Dergi Adı: JOURNAL OF DENTISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.364-371
Gazi Üniversitesi Adresli: Evet

Özet

Objectives: Systemic conditions may affect host susceptibility, disease progression and severity as well as treatment response. Previously, low oestrogen (E-2) levels were associated with increased bone resorption, due to increased osteoclastogenesis and decreased osteoclast apoptosis. Osteoprotegerin (OPG) is an essential cytokine for osteoclastogenesis. The aim of this study was to evaluate gingival crevicular fluid (GCF) OPG levels in menopausal and premenopausal patients with or without periodontitis, and effects of phase I periodontal therapy on GCF OPG levels.