EFFECTS OF MELOXICAM, ALONE AND IN COMBINATION WITH CHEMOTHERAPEUTIC AGENTS ON THE RAF/MEK/ERK PATHWAY IN RAJI CELLS


ÖNEN H. İ. , Yilmaz A., Alp E., YAR SAĞLAM A. S. , KONAÇ E. , Menevse S.

ACTA MEDICA MEDITERRANEA, cilt.30, sa.3, ss.717-723, 2014 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Konu: 3
  • Basım Tarihi: 2014
  • Dergi Adı: ACTA MEDICA MEDITERRANEA
  • Sayfa Sayıları: ss.717-723

Özet

Background: Non-steroidal anti-inflammatory drugs (NSAIDs) have been reported to induce apoptosis and inhibit cell proliferation in tumor cells when combined with conventional chemotherapeutic agents. We aimed to investigate the effect of NSAIDs (meloxicam and lornoxicam) plus conventional chemotherapeutic agents on RAF/MEK/ERK pathway in Burkitt's lymphoma cell line (Raji).