Association of serum levels of IGF-I and IGFBP-1 with renal function in patients with type 2 diabetes mellitus.


Akturk M., Arslan M., Altinova A., Ozdemir A., Ersoy R., Yetkin I., ...Daha Fazla

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, cilt.17, sa.3, ss.186-93, 2007 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Konu: 3
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.ghir.2007.01.007
  • Dergi Adı: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
  • Sayfa Sayıları: ss.186-93

Özet

Objective: Our aim was to determine whether serum Insulin-like growth factor-I (IGF-I) and Insulin-like growth factor binding protein-1 (IGFBP-1) levels were different between type 2 diabetic patients and non-diabetic control group. We also aimed to establish any relationship that might exist between the serum IGF-I and IGFBP-1 levels with the urinary albumin excretion (UAE), creatinine clearance and urinary N-acetyl-beta-D-glucosaminidase (NAG) excretion (as a marker of renal tubular dysfunction) and other parameters (such as age, duration of diabetes, treatment, etc.) in patients with type 2 diabetes mellitus (DM).