GROWTH HORMONE & IGF RESEARCH, vol.17, no.3, pp.186-193, 2007 (Journal Indexed in SCI)
Article / Article
Title of Journal :
GROWTH HORMONE & IGF RESEARCH
type 2 diabetes, insulin-like growth factor-I, insulin-like growth factor binding protein-1, creatinine clearance, urinary N-acetyl-beta-D-glucosaminidase, GROWTH-FACTOR-I, FACTOR BINDING PROTEIN-1, GLOMERULAR-FILTRATION-RATE, FACTOR SYSTEM COMPONENTS, CARDIOVASCULAR RISK, INSULIN, MICROALBUMINURIA, CHILDREN, FAILURE, DISEASE
Objective: Our aim was to determine whether serum Insulin-like growth factor-I (IGF-I) and Insulin-like growth factor binding protein-1 (IGFBP-1) levels were different between type 2 diabetic patients and non-diabetic control group. We also aimed to establish any relationship that might exist between the serum IGF-I and IGFBP-1 levels with the urinary albumin excretion (UAE), creatinine clearance and urinary N-acetyl-beta-D-glucosaminidase (NAG) excretion (as a marker of renal tubular dysfunction) and other parameters (such as age, duration of diabetes, treatment, etc.) in patients with type 2 diabetes mellitus (DM).