Effect of tyrosine-rich amelogenin peptide on behavior and differentiation of endothelial cells


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Jonke E., Gemperli A. C. , Zhang T., Ozdemir B. , Dard M., Rausch-Fan X., ...Daha Fazla

CLINICAL ORAL INVESTIGATIONS, cilt.20, sa.8, ss.2275-2284, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Konu: 8
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1007/s00784-016-1726-2
  • Dergi Adı: CLINICAL ORAL INVESTIGATIONS
  • Sayfa Sayıları: ss.2275-2284

Özet

Enamel matrix derivative (EMD) is an effective biomaterial for periodontal tissue regeneration and might stimulate angiogenesis. Tyrosine-rich amelogenin peptide (TRAP) is present in EMD and is thought to contribute in its biological activity. In the present study, we investigated the effect of chemically synthesized TRAP on proliferation, migration, angiogenic structure formation, and differentiation of human umbilical vein endothelial cells (HUVECs) in vitro.