Phylogenetic and Evolutionary Analyses of the VP4 Gene of P[9] Rotaviruses

Ahmed S., Yahiro T., Emran N. A., Amit L. N., Iha H., BOZDAYI G., ...Daha Fazla

GAZI MEDICAL JOURNAL, cilt.32, sa.4A, ss.638-646, 2021 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 4A
  • Basım Tarihi: 2021
  • Doi Numarası: 10.12996/gmj.2021.145
  • Dergi Adı: GAZI MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier
  • Sayfa Sayıları: ss.638-646
  • Anahtar Kelimeler: Rotavirus, genotype P[9], phylogenetic analysis, lineages, time-line of evolution, RNA-RNA HYBRIDIZATION, RARE HUMAN, STRAINS, CHILDREN, FELINE, GENOTYPE, DIARRHEA, IDENTIFICATION, PREDOMINANCE, REASSORTMENT
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: Rotavirus is one of the major causes of gastroenteritis in children under 5 years of age. It can evolve by reassortment, in which gene segments are exchanged between strains of different origins. In some rotavirus strains the P[ 9] component is an example of reassortment, in which the P[9] genotype is from feline species. A number of outbreaks associated with P[9] strains have been documented in several countries. However, details regarding the epidemiological relationships between the strains remains largely unknown. Therefore, in the present study, genetic characterization and evolutionary analyses were performed to gain insight into P[9] strains circulating in different parts of the world.