One-pot and multi-step syntheses of new 2-(4,5-dihydro-1H-pyrazol-1-yl) thiazole derivatives


GÜMÜŞ M., DİŞLİ A. , Yakan M., Yigitcan S., KOCA İ.

ORGANIC COMMUNICATIONS, cilt.11, sa.2, ss.98-110, 2018 (ESCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Konu: 2
  • Basım Tarihi: 2018
  • Doi Numarası: 10.25135/acg.oc.40.18.03.071
  • Dergi Adı: ORGANIC COMMUNICATIONS
  • Sayfa Sayıları: ss.98-110

Özet

beta-Ketoester and ethanone derivatives, potentially functional molecules, containing the pyrazole/thiazole scaffolds were synthesized. The structures of the synthesized novel compounds were confirmed by FTIR, H-1 NMR and C-13 NMR spectroscopy and elemental analysis. The NMR spectra of the synthesized compounds are analyzed. Furthermore, ABX systems in pyrazole ring were studied in detail and the coupling constants of the diastereotopic protons.