The prognostic value of p53 and c-erbB-2 expression, proliferative activity and angiogenesis in node-negative breast carcinoma

ERDEM O. A., Dursun A., Coskun U., Gunel N.

TUMORI J, cilt.91, sa.1, ss.46-52, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 91 Sayı: 1
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1177/030089160509100109
  • Dergi Adı: TUMORI J
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.46-52
  • Anahtar Kelimeler: angiogenesis c-erbB-2, Ki-67, lymph node-negative breast carcinoma, p53, STEROID-HORMONE RECEPTORS, C-ERB B-2, CELL-PROLIFERATION, PROTEIN EXPRESSION, TUMOR ANGIOGENESIS, CANCER, SURVIVAL, AMPLIFICATION, GENE
  • Gazi Üniversitesi Adresli: Evet

Özet

Aims and background. p53, c-erbB-2 and Ki-67 protein expression and microvessel density (MVD) determined by CD34 antibody were evaluated by immunohistochemistry and their correlation with clinicopathological parameters including estrogen (ER) and progesterone (PR) receptor status and survival were investigated in patients with axillary lymph node-negative infiltrating ductal breast carcinoma.