Gingival crevicular fluid prostaglandin E-2 and thiobarbituric acid reactive substance levels in smokers and non-smokers with chronic periodontitis following phase I periodontal therapy and adjunctive use of flurbiprofen

Kurtis, MAZLUM; Tuter, GÜLAY; SERDAR, Muhittin; Pinar, Selin; Demirel, Ilkim; Toyman, Utku

doi:10.1902/jop.2007.060217

Gingival crevicular fluid prostaglandin E-2 and thiobarbituric acid reactive substance levels in smokers and non-smokers with chronic periodontitis following phase I periodontal therapy and adjunctive use of flurbiprofen

Kurtis B., Tuter G., SERDAR M. A., Pinar S., Demirel I., Toyman U.

JOURNAL OF PERIODONTOLOGY, cilt.78, sa.1, ss.104-111, 2007 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 78 Sayı: 1
Basım Tarihi: 2007
Doi Numarası: 10.1902/jop.2007.060217
Dergi Adı: JOURNAL OF PERIODONTOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.104-111
Anahtar Kelimeler: chronic periodontitis, flurbiprofen/therapeutic use, gingival crevicular fluid, prostaglandin E-2, smoking, thiobarbituric acid reactive substances, NONSTEROIDAL ANTIINFLAMMATORY DRUGS, MATRIX METALLOPROTEINASE-8, DISEASE PROGRESSION, CIGARETTE-SMOKING, TNF-ALPHA, EXPRESSION, INTERLEUKIN-1-BETA, ANTIOXIDANTS, DOXYCYCLINE, INHIBITION
Gazi Üniversitesi Adresli: Evet

Özet

Background: It has been established that smoking is an important risk factor for the initiation and progression of chronic periodontitis (CP). This study investigates the effects of phase I periodontal therapy and adjunctive flurbiprofen administration on prostaglandin E-2 (PGE(2)) and thiobarbituric acid reactive substance (TBARS) levels in gingival crevicular fluid (GCF) samples from smoker and non-smoker patients with CP.