Effects of melatonin on cytokine release and healing of colonic anastomoses in an experimental sepsis model


Ersoy O. F. , Ozkan N., ÖZSOY Z., Kayaoglu H. A. , Yenidogan E., Celik A., ...More

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, vol.22, no.4, pp.315-321, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 4
  • Publication Date: 2016
  • Doi Number: 10.5505/tjtes.2015.49465
  • Journal Name: ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.315-321
  • Keywords: Anastomosis, colon, melatonin, sepsis, C-REACTIVE PROTEIN, NF-KAPPA-B, NECROSIS-FACTOR-ALPHA, OXIDATIVE STRESS, RAT MODEL, PERITONITIS, ACTIVATION, INJURY, TISSUE, GENE
  • Gazi University Affiliated: Yes

Abstract

BACKGROUND: The present objective was to identify effects of early melatonin application on healing of anastomotic wound and inflammation in an experimental sepsis model.