Good practice recommendations on spontaneous preterm birth
European Journal of Obstetrics and Gynecology and Reproductive Biology, cilt.326, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 326
- Basım Tarihi: 2026
- Doi Numarası: 10.1016/j.ejogrb.2026.115389
- Dergi Adı: European Journal of Obstetrics and Gynecology and Reproductive Biology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE, Academic Search Ultimate (EBSCO)
- Anahtar Kelimeler: Antenatal corticosteroids, Cerclage, Cervical length, Europe, Microbiome, Neonatal resuscitation, Preterm birth, Progesterone
- Gazi Üniversitesi Adresli: Evet
Özet
Preterm birth continues to affect 5 to 12% of all live births in Europe and remains a leading cause of neonatal mortality and short- and long-term morbidity. Despite decades of research and clinical innovation, the overall burden has not substantially declined, and in several European settings rates are rising. This paper is a European Association of Perinatal Medicine (EAPM) Good Practice Recommendation which synthesises current evidence on spontaneous PTB (sPTB) risk and management, and examines why preterm birth persists as a clinical and public health challenge. We review the epidemiology, classification, and aetiology of sPTB; the role of the maternal microbiome; evidence-based preventive strategies; perinatal management; and neonatal care. We highlight the importance of a multicomponent and evidence-based approach, focusing on primary, secondary and tertiary prevention, to reduce the human and societal cost of preterm birth across Europe.