THE EFFECT OF BETA-CYCLODEXTRIN AND PENETRATION ADDITIVES ON THE RELEASE OF NAPROXEN FROM OINTMENT BASES


CELEBI N., KISLAL O., TARIMCI N.

PHARMAZIE, cilt.48, ss.914-917, 1993 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 48 Konu: 12
  • Basım Tarihi: 1993
  • Dergi Adı: PHARMAZIE
  • Sayfa Sayıları: ss.914-917

Özet

The in vitro release of naproxen (1) from various ointment bases; including gel base, University of California Hospital base (UCH) and water-washable emulsion base were studied. The effect of beta-cyclodextrin (beta-CD) and penetration additives (propylene glycol and dimethyl sulfoxide, DMSO) on the release rate of the drug were investigated.