Timing of myocardial shortening determines left ventricular regional myocardial work and regional remodelling in hearts with conduction delays

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Cvijic M., Duchenne J., Unlu S., Michalski B., Aarones M., Winter S., ...More

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, vol.19, no.8, pp.941-949, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 8
  • Publication Date: 2018
  • Doi Number: 10.1093/ehjci/jex325
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.941-949
  • Keywords: myocardial shortening, wall thickness, dys-synchrony, left ventricular stress-strain loop, myocardial work, cardiac resynchronization therapy, CARDIAC RESYNCHRONIZATION THERAPY, BUNDLE-BRANCH BLOCK, FAILURE PATIENTS, WALL THICKNESS, DYSSYNCHRONY, ACTIVATION, EXPRESSION, MASS, CRT
  • Gazi University Affiliated: No


Aims The interaction between asynchronous regional myocardial activation and left ventricular (LV) wall remodelling has not been well established. We investigated the relationship between time of onset of longitudinal shortening (Tonset), regional myocardial work, and segmental LV wall thickness (SWT) in patients treated with cardiac resynchronization therapy (CRT).